2018,    N 3 (33)    

VETERINARY SCIENCE AND ANIMAL INDUSTRIES

Lashin A., Simonova N., Gavrilov Yu., Khibchenov L., Chubin A., Trush N.

Phytomedication in correction of antioxidant status newborn calves

Currently, in clinical practice, phytoadaptogens with antioxidant and cytoprotective properties are used as pharmacologically active substances with a wide range of biological effects. Under the experimental conditions, the possibility of correcting the free radical lipid oxidation of the membranes of the calf organism by oral administration of phytoadaptogens containing a complex of natural antioxidants was investigated. The animals were divided into 4 groups, each containing 10 calves: a control group, the animals were kept under standard conditions; experimental group, where animals were given oral ginseng tincture in a dose of 5 ml per day; experimental group, where animals were daily administered per os tincture of magnolia vine in a dose of 5 ml; The experimental group, where the animals were daily administered orally with tincture of aralia in a dose of 5 ml. It has been established that the introduction of phytoadaptogens to calves helps reduce blood lipid hydroperoxides by 15 - 32% in blood plasma, 11 - 25% in dienic conjugates, and 17-27% in malonic dialdehyde in comparison with calves of the control group. When analyzing the effect of phytoadaptogens on the activity of components of the antioxidant system, it was found that the content of ceruloplasmin in the blood of animals was significantly higher than in the control group calves by 23-29%, vitamin E by 12-24%. Thus, the use of these phytoadaptogens results in the stabilization of peroxidation processes against the background of an increase in the activity of the main components of the antioxidant system.

Keywords: PHYTOADAPTOGEN, PEROXIDATION OF LIPIDS OF BIOLOGICAL MEMBRANES, ANTIOXIDANT SYSTEM, TELATE